VOTE THE BLUE UNIVERSAL CARD

ONLY VOTE 1 CARD. DISCARD THE WHITE CARD

Your vote at Alkermes’ Annual General Meeting of Shareholders on June 29, 2023 is very important.

We urge all shareholders to vote “FOR” the election of the Sarissa Nominees, “AGAINST” the compensation of the Company’s named executive officers, and “FOR” all other proposals in our proxy statement.

You can vote in one of three easy ways: by internet at www.cesvote .com, by telephone at 1-888-693-8683 or by mail using the BLUE universal proxy card and postage-paid envelope sent to you.

If you vote by internet or telephone, you will be required to provide the unique control number printed on your BLUE universal proxy card.

If you have any questions regarding your BLUE proxy card or need assistance in executing your proxy card, please contact:

D.F. King & Co., Inc. 48 Wall Street
Shareholders call toll-free: (866) 207-3648
Brokers and Banks call: (212) 493-6952
Email: [email protected]

SARISSA PRESENTATIONS

Presentation Slides Dated – June 26, 2023

Presentation Slides Dated – June 15, 2023

Presentation Slides Dated – June 9, 2023

Presentation Slides Dated – June 6 , 2023

SARISSA PUBLIC STATEMENTS

June 28, 2023 – Sarissa Capital Urges Alkermes Shareholders To Vote “For” Sarah Schlesinger And “Withhold” Incumbent Director Richard Gaynor

June 26, 2023 – Sarissa Issues Presentation Highlighting Sarissa Nominees Are Qualified To Create Value For Alkermes Shareholders

June 22, 2023 – Independent Proxy Advisory Firm ISS Agrees With Sarissa Capital That Shareholders’ Interests Would Be Best Served With Direct Shareholder Representation On The Alkermes Board

June 20, 2023 – Independent Proxy Advisory Firm ISS Concludes That Sarissa Capital Has Made A Compelling Case For Change To The Alkermes Board

June 15, 2023 – Sarissa Issues Presentation Highlighting The Need For Shareholder Representation On The Alkermes Board

June 13, 2023 – Sarissa Urges Shareholders To Vote For Sarissa Nominees To Provide Much Needed Oversight And Accountability To Alkermes

June 9, 2023 – Sarissa Capital Highlights Misleading Claims Made By Alkermes In Its Attempt To Thwart Shareholder Representation On The Board

June 5, 2023 – Sarissa Urges Alkermes Shareholders To Vote The Universal Blue Card To Upgrade Alkermes For The Benefit Of Shareholders

VOTE THE BLUE UNIVERSAL CARD

ONLY VOTE 1 CARD. DISCARD THE WHITE CARD

Your vote at Alkermes’ Annual General Meeting of Shareholders on June 29, 2023 is very important.

We urge all shareholders to vote “FOR” the election of the Sarissa Nominees, “AGAINST” the compensation of the Company’s named executive officers, and “FOR” all other proposals in our proxy statement.

You can vote in one of three easy ways: by internet at www.cesvote .com, by telephone at 1-888-693-8683 or by mail using the BLUE universal proxy card and postage-paid envelope sent to you.

If you vote by internet or telephone, you will be required to provide the unique control number printed on your BLUE universal proxy card.

If you have any questions regarding your BLUE proxy card or need assistance in executing your proxy card, please contact:

SARISSA PRESENTATIONS

SARISSA PUBLIC STATEMENTS

SARISSA PROXY STATEMENT

SARISSA NOMINEES

#UPGRADEALKERMES

UPGRADE ALKERMES

VOTE THE BLUE UNIVERSAL CARD

ONLY VOTE 1 CARD. DISCARD THE WHITE CARD

Your vote at Alkermes’ Annual General Meeting of Shareholders on June 29, 2023 is very important.

We urge all shareholders to vote “FOR” the election of the Sarissa Nominees, “AGAINST” the compensation of the Company’s named executive officers, and “FOR” all other proposals in our proxy statement.

You can vote in one of three easy ways: by internet at www.cesvote.com, by telephone at 1-888-693-8683 or by mail using the BLUE universal proxy card and postage-paid envelope sent to you.

If you vote by internet or telephone, you will be required to provide the unique control number printed on your BLUE universal proxy card.

If you have any questions regarding your BLUE proxy card or need assistance in executing your proxy card, please contact:

SARISSA PRESENTATIONS

SARISSA PUBLIC STATEMENTS

SARISSA PROXY STATEMENT

SARISSA NOMINEES

#UPGRADEALKERMES

You can vote in one of three easy ways: by internet at www.cesvote .com, by telephone at 1-888-693-8683 or by mail using the BLUE universal proxy card and postage-paid envelope sent to you.